Description

GLP-2 (Also known as Tirzepatide) is a synthetic 39-amino acid peptide that acts as a first-in-class dual agonist for both the GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors. Known as a “twincretin,” this compound is designed for high-purity laboratory research into synergistic metabolic pathways, glycemic regulation, and adipose tissue signaling.

• Purity: >99% (HPLC Tested)

• Format: Lyophilized White Powder

• Molecular Formula: $C_{225}H_{348}N_{48}O_{68}$

• Research Target: Dual-Pathway Incretin Mimicry

Tirzepatide represents a significant advancement in metabolic research by combining the properties of two essential incretin hormones into a single molecular structure. While traditional research focused on single GLP-1 receptor agonists, Tirzepatide’s dual-agonist profile allows for a more comprehensive investigation into how GIP and GLP-1 work together to regulate insulin secretion, delay gastric emptying, and influence central appetite signaling.

Research Observed Outcomes

Data derived from the SURMOUNT and SURPASS research programs highlight the following physiological impacts in controlled test models:

• 20.9% Weight Reduction: In 72-week controlled trials, the 15mg dose resulted in an average body weight reduction of 20.9%.

• 2.3% HbA1c Reduction: Research in Type 2 Diabetes (T2D) models demonstrated an average 2.3% reduction in A1c levels.

• Cardiovascular Markers: Studies indicate a 33.9% reduction in triglycerides and a mean systolic blood pressure reduction of 12.6 mmHg.

• Metabolic Impact: Exploratory research showed a relative liver fat reduction of 39.6% in subjects with fatty liver models.

• Insulin Sensitivity: Fasting insulin levels decreased by up to 46.6%, indicating a significant increase in insulin sensitivity.

Storage & Stability Protocols

To maintain peptide integrity and prevent degradation, the following storage guidelines are recommended:

• Lyophilized Powder: Store at -20°C for long-term stability. Stable at room temperature for short-term transit.

• Reconstituted Stability (Bacteriostatic Water): Once reconstituted, the solution typically maintains stability for 4–6 weeks when refrigerated (2°C – 8°C).

• Reconstituted Stability (Sterile Water): Stability is significantly shorter, typically 7–12 days, due to the absence of antimicrobial preservatives.

• Handling: Research personnel should follow manufacturer guidelines and avoid repeated freeze-thaw cycles.

⚠️ STRICT COMPLIANCE NOTICE: FOR LABORATORY RESEARCH ONLY This product is a chemical substance intended strictly for in vitro or laboratory experimentation. Any form of ingestion, injection, or topical application to humans or animals is STRICTLY PROHIBITED. This product is not a drug, food, or cosmetic and has not been approved by the FDA for any medical application. Handling should only be performed by qualified professionals in a controlled environment.