Description

PT-141 (Bremelanotide) – 10mg

PT-141, also known as Bremelanotide, is a synthetic cyclic heptapeptide derived from Melanotan II. It is studied in laboratory settings for its selective activation of melanocortin receptors, particularly MC3R and MC4R, which are involved in central nervous system signaling pathways.

This peptide is engineered strictly for laboratory investigation into melanocortin receptor biology, neuroendocrine signaling, and central dopaminergic pathway modulation.

Purity: >99% (HPLC Tested)
Format: Lyophilized White Powder
Molecular Formula: C50H68N14O10
Research Target: Melanocortin Receptors (MC3R / MC4R) & CNS Signaling

PT-141 functions by binding to melanocortin receptors in experimental models, influencing neural pathways distinct from vascular-mediated mechanisms. Unlike phosphodiesterase inhibitors, PT-141 is studied for central receptor activation rather than peripheral vasodilation, making it a focused compound in neuroendocrine research.

Research Observed Outcomes

Data from neurobiological and endocrine research programs highlight the following findings in controlled laboratory models:

Melanocortin Receptor Activation:
PT-141 demonstrates selective activation of MC3R and MC4R receptors in central nervous system research models.

Neuroendocrine Signaling Modulation:
Laboratory studies suggest influence on dopaminergic and hypothalamic pathways associated with behavioral signaling.

Appetite & Energy Regulation Research:
Melanocortin receptor pathways are studied for their role in appetite control and energy balance modulation.

Minimal Peripheral Vascular Interaction:
Research indicates primary central activity compared to earlier melanocortin analogs with stronger pigmentation effects.

Pigmentation Pathway Research:
While derived from Melanotan II, PT-141 demonstrates reduced melanogenic activation relative to broader melanocortin agonists in controlled settings.

Key Linked Studies & Research References

Melanocortin Receptor Biology:
Cone, R.D. (2005). “Anatomy and regulation of the central melanocortin system.” Nature Neuroscience.

PT-141 Pharmacology:
King, S.H., et al. (2000). “Melanocortin receptor agonists and sexual behavior research.” Journal of Clinical Endocrinology & Metabolism.

MC4R & Energy Balance:
Mountjoy, K.G., et al. (1992). “The melanocortin receptor family.” Science.

Neuroendocrine Modulation Research:
Pfaus, J.G., et al. (2004). “Central melanocortin receptor activation.” Neuroscience & Biobehavioral Reviews.

Storage & Stability Protocols

To preserve peptide structure and receptor-binding integrity:

Lyophilized Powder:
Store at -20°C for long-term stability. Stable at room temperature for short-term transit.

Reconstituted Stability (Bacteriostatic Water):
When reconstituted under sterile laboratory conditions, solution stability is typically maintained for 4–6 weeks under refrigeration (2°C – 8°C).

Reconstituted Stability (Sterile Water):
Stability is significantly shorter, typically 7–12 days due to absence of antimicrobial preservatives.

Handling:
Avoid repeated freeze-thaw cycles. Protect from excessive heat, light, and agitation during reconstitution.

⚠️ STRICT COMPLIANCE NOTICE: FOR LABORATORY RESEARCH ONLY
This product is a chemical research peptide intended strictly for in vitro or laboratory experimentation. Any form of ingestion, injection, or topical application to humans or animals is STRICTLY PROHIBITED. This product is not a drug, food, or cosmetic and has not been approved by the FDA for any medical application. Handling must be performed by qualified professionals in controlled laboratory environments.