Description

Glutathione is a naturally occurring tripeptide composed of glutamine, cysteine, and glycine. It functions as a primary intracellular antioxidant and redox regulator in cellular research. Reduced L-Glutathione (GSH) is widely studied for its role in oxidative stress modulation, mitochondrial protection, detoxification pathways, and cellular defense mechanisms.

This compound is engineered exclusively for laboratory investigation into oxidative balance, mitochondrial function, and cellular resilience under metabolic stress conditions.

Purity: >99% (HPLC Tested)
Format: Lyophilized White Powder
Molecular Formula: C10H17N3O6S
Research Target: Oxidative Stress Regulation & Redox Balance

Glutathione is central to intracellular antioxidant systems. In laboratory models, it acts as a cofactor for glutathione peroxidase and plays a critical role in neutralizing reactive oxygen species (ROS). It is heavily studied in mitochondrial research due to its function in protecting cellular membranes, DNA, and proteins from oxidative damage.

Research Observed Outcomes

Data from cellular and metabolic research programs highlight the following findings in controlled laboratory models:

Reduction of Oxidative Stress:
Glutathione supplementation in cellular models significantly reduces reactive oxygen species and lipid peroxidation markers.

Mitochondrial Protection:
Research indicates improved mitochondrial membrane stability and preservation of ATP production under oxidative challenge conditions.

Detoxification Support:
Glutathione plays a central role in Phase II conjugation pathways, supporting cellular detoxification mechanisms in hepatic research models.

Inflammatory Marker Modulation:
Laboratory data suggests glutathione may reduce oxidative-driven inflammatory signaling cascades.

Cellular Longevity Research:
Declines in endogenous glutathione levels are associated with aging in research models. Restoration of intracellular GSH is studied for its potential role in cellular resilience and longevity pathways.

Key Linked Studies & Research References

Redox Biology & Antioxidant Function:
Wu, G., et al. (2004). “Glutathione metabolism and its implications for health.” Journal of Nutrition.

Mitochondrial Protection:
Mari, M., et al. (2009). “Mitochondrial glutathione: features, regulation, and role in disease.” Antioxidants & Redox Signaling.

Oxidative Stress & Aging:
Lushchak, V.I. (2014). “Free radicals, reactive oxygen species, oxidative stress and its classification.” Chemico-Biological Interactions.

Detoxification Mechanisms:
Townsend, D.M., et al. (2003). “The importance of glutathione in human disease.” Biomedicine & Pharmacotherapy.

Storage & Stability Protocols

To preserve structural integrity and antioxidant activity:

Lyophilized Powder:
Store at -20°C for long-term stability. Protect from moisture and light exposure.

Reconstituted Stability (Bacteriostatic Water):
When prepared under sterile laboratory conditions, stability is typically maintained for up to 4–6 weeks under refrigeration (2°C – 8°C).

Reconstituted Stability (Sterile Water):
Stability is significantly shorter, typically 7–10 days, due to the absence of antimicrobial preservatives.

Handling:
Glutathione is sensitive to oxidation. Minimize exposure to air, heat, and light. Avoid vigorous shaking during reconstitution.

⚠️ STRICT COMPLIANCE NOTICE: FOR LABORATORY RESEARCH ONLY
This product is a chemical substance intended strictly for in vitro or laboratory experimentation. Any form of ingestion, injection, or topical application to humans or animals is STRICTLY PROHIBITED. This product is not a drug, food, or cosmetic and has not been approved by the FDA for any medical application. Handling must be performed by qualified professionals in controlled laboratory environments.