Description

TB-500 (Thymosin Beta-4 Fragment) – 10mg

TB-500 is a synthetic research peptide modeled after Thymosin Beta-4, a naturally occurring actin-binding protein present in most human and animal cells. It is studied in laboratory settings for its role in cytoskeletal regulation, cellular migration, angiogenesis signaling, and tissue repair pathways.

This peptide is engineered strictly for laboratory investigation into wound healing models, connective tissue regeneration research, and inflammatory modulation mechanisms.

Purity: >99% (HPLC Tested)
Format: Lyophilized White Powder
Molecular Formula: C212H350N56O78S
Research Target: Actin Regulation & Cellular Migration Pathways

TB-500 functions by influencing actin polymerization, a fundamental process in cell movement and structural repair. In experimental models, it has demonstrated regulatory effects on angiogenic signaling and extracellular matrix remodeling, making it a primary compound in tissue recovery research.

Research Observed Outcomes

Data from preclinical and cellular research programs highlight the following findings in controlled laboratory models:

Enhanced Cellular Migration:
TB-500 has been shown to promote fibroblast and endothelial cell migration in wound healing models.

Angiogenesis Modulation:
Laboratory investigations demonstrate increased vascular formation markers in tissue injury studies.

Reduced Inflammatory Markers:
Research suggests downregulation of pro-inflammatory cytokine expression in experimental tissue stress models.

Connective Tissue Regeneration Research:
Preclinical studies observed improved tendon and ligament repair markers in musculoskeletal injury models.

Cytoskeletal Stabilization:
TB-500 influences actin dynamics, supporting structural cellular integrity during recovery phases.

Key Linked Studies & Research References

Thymosin Beta-4 Mechanism:
Goldstein, A.L., et al. (2005). “Thymosin beta-4: Actin-sequestering and tissue repair properties.” Annals of the New York Academy of Sciences.

Wound Healing Research:
Malinda, K.M., et al. (1999). “Thymosin beta-4 accelerates wound healing.” FASEB Journal.

Angiogenesis Studies:
Smart, N., et al. (2007). “Thymosin beta-4 and cardiac repair.” Nature.

Inflammatory Modulation Research:
Sosne, G., et al. (2004). “Thymosin beta-4 reduces inflammatory cytokine expression.” Journal of Immunology.

Storage & Stability Protocols

To preserve peptide structure and bioactivity:

Lyophilized Powder:
Store at -20°C for long-term stability. Stable at room temperature for short-term transit.

Reconstituted Stability (Bacteriostatic Water):
When reconstituted under sterile laboratory conditions, solution stability is typically maintained for 4–6 weeks under refrigeration (2°C – 8°C).

Reconstituted Stability (Sterile Water):
Stability is significantly shorter, typically 7–12 days due to absence of antimicrobial preservatives.

Handling:
Avoid repeated freeze-thaw cycles. Protect from excessive heat, light, and agitation during reconstitution.

⚠️ STRICT COMPLIANCE NOTICE: FOR LABORATORY RESEARCH ONLY
This product is a chemical research peptide intended strictly for in vitro or laboratory experimentation. Any form of ingestion, injection, or topical application to humans or animals is STRICTLY PROHIBITED. This product is not a drug, food, or cosmetic and has not been approved by the FDA for any medical application. Handling must be performed by qualified professionals in controlled laboratory environments.